DHT plays a major role in hair loss. DHT stands for Dihydrotestosterone (5α-Dihydrotestosterone). A male sex hormone, an androgen. 5α-reductase, an enzyme, synthesizes DHT in the adrenal glands, hair follicles, testes and prostate.
Testosterone converts to DHT with the aid of the enzyme Type II
5-alpha reductase, which is held in a hair follicle's oil glands (sebaceous).
Scientists now believe that it's not the amount of circulating
testosterone that's the problem but the level of DHT binding to
receptors in scalp follicles. DHT shrinks hair follicles, making it
impossible for healthy hair to survive.
The hormonal process of testosterone converting to DHT, which then
harms hair follicles, happens in both men and women. Under normal
conditions, women have a minute fraction of the level of testosterone
that men have, but even a lower level can cause DHT- triggered hair loss
in women. And certainly when those levels rise, DHT is even more of a
problem. Those levels can rise and still be within what doctors consider
"normal" on a blood test, even though they are high enough to cause a
problem. The levels may not rise at all and still be a problem if you
have the kind of body chemistry that is overly sensitive to even its
regular levels of chemicals, including hormones.
Source: American Hair Loss Association